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Effects and dependency - G (GHB and GBL)

GHB (gamma hydroxybutyrate) is a chemical that slows down messages between your brain and body. It can make you feel relaxed, turned on or confused.

GBL (gamma butyrolactone) and BD (1,4-butanediol) are similar chemicals. Your body converts them to GHB when you swallow them.

GHB, GBL and BD may all be called G.

G comes as:

  • clear liquid in a small bottle
  • powder - but this is rare

You swallow the liquid mixed with water or a soft drink. A dose that causes mild effects in some people can cause an overdose in other people.

Information:

It is very easy to overdose on G. G is very strong in small amounts. The difference between an amount that causes mild effects and a dangerous amount is less than 1 millilitre.

Drug category: depressant

Depressants slow down messages between your brain and body. They can make you feel relaxed and drowsy. They also affect your breathing, memory and coordination.

Other names for G

Other names include: 1,4-BD, GBH, gina, liquid E, liquid ecstasy, liquid X

Effects of G

The effects of G can vary depending on:

  • your size, weight and sex
  • if you have any health conditions or mental health difficulties
  • how you take the drug
  • the strength of the drug
  • how much you take
  • if you take alcohol, medicines or other drugs at the same time
  • where you take the drug and how you feel before you take it
  • if you have taken the drug before and how often

The effects can start after 20 minutes and can last up to 4 hours.

How you may feel or behave

You may feel:

  • relaxed and calm
  • intense wellbeing or happiness (euphoria)
  • confident and social
  • confused, anxious or paranoid
  • aggressive
  • affectionate or turned on

Effects on your brain and body

G can cause:

  • drowsiness or dizziness
  • nausea (feeling sick)
  • vomiting (getting sick)
  • muscle spasms or convulsions
  • breathing problems
  • lower inhibitions - you may do things you usually would not do
  • increased sex drive or sexual arousal
  • problems concentrating
  • burns in your mouth or throat - if you do not mix it with another liquid
  • problems controlling your body
  • seizures (fits)
  • hallucinations - you may see or hear things that are not there
  • loss of consciousness or coma (going under) - this is a medical emergency
  • overdose

G and sex

People may use G during sex or chemsex to:

  • feel more pleasure
  • lower inhibitions or feel more confident
  • make sex last longer
  • relax muscles for anal sex or fisting

Drugs and sex

G and mental health

G can cause mental health difficulties or make existing difficulties worse.

Regular use of G can lead to:

  • anxiety
  • depression
  • mood swings or aggression
  • paranoia
  • thoughts of suicide
  • psychosis - you have confused thoughts, feelings and behaviour and you do not know what is real or not real

G and dependency

G can quickly cause:

  • tolerance - when you need to take more of the drug to get the same effects
  • dependency

Signs of dependency can include:

  • cravings for a drug
  • withdrawal symptoms
  • continuing to use a drug even when it causes you harm

You can still overdose on G if you have developed a tolerance or dependency.

It is not safe to suddenly stop taking G after regular use. This is because it can cause seizures or death.

If you want to stop, you can get support from:

  • your GP or practice nurse
  • a drug service
  • our club drug clinic

Non-urgent advice: Drugs and alcohol helpline

You can contact the helpline for support, information or advice on treatment and support options.

Freephone: 1800 459 459
Monday to Friday, 9.30am to 5.30pm

Email: helpline@hse.ie

Withdrawal from G

Withdrawal symptoms from G can start 1 to 2 hours after your last dose.

Withdrawal symptoms include:

  • anxiety or paranoia
  • shaking
  • problems sleeping
  • nausea and vomiting
  • sweating
  • confusion or agitation
  • feeling of skin crawling
  • hallucinations - you may see, feel or hear things that are not there
  • seizures (fits)
  • psychosis
  • increased heart rate and breathing rate
  • fever

Withdrawal from G can be serious.

Get medical help if you have these symptoms. Do not suddenly stop taking G.

Emergency action required: Go to your nearest emergency department (ED) if

you have no G and you:

  • take G often
  • have symptoms of withdrawal

Tell the medics you take G. It is the safest thing to do.

How long does G stay in your system?

It can be hard to know how long G stays in your system.

There are tests to detect G. But different types of tests have different detection times.

Things that affect how long a drug stays in your system

The time it takes for a drug to leave your system depends on many things.

For example:

  • how much you took
  • how often you take the drug
  • how strong the drug was
  • your age, sex and metabolism
  • your general health

Page last reviewed: 24/11/2025
Next review due: 24/11/2028

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