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Side effects

AstraZeneca COVID-19 vaccine

Like all medicines, vaccines can cause side effects. Most of these are mild to moderate and short-term. Not everyone gets side effects.

If you are concerned about side effects, phone your GP for advice.

Common side effects

The common side effects after all the COVID-19 vaccines happen less often in people aged 65 and older. 

After the AstraZeneca COVID-19 vaccine, more than 1 in 10 people may experience:

  • feeling tired
  • tenderness, bruising, pain, redness or itching in the arm where they had the vaccine injection
  • headache
  • muscle pain
  • joint pain
  • nausea, diarrhoea or vomiting
  • fever (temperature of 38 degrees Celsius or above)

The common side effects after the AstraZeneca vaccine are more likely after the first dose of vaccine.

More than one in 100 people may have redness or swelling where they had the injection.

Rare side effects

After the AstraZeneca COVID-19 vaccine, more than 1 in 1,000 people may experience:

  • reduced appetite
  • dizziness
  • sleepiness
  • sweating
  • swollen lymph glands
  • rash

Very rare cases of unusual blood clots along with low levels of blood platelets have been seen in less than 1 in 100,000 people after vaccination with the AstraZeneca COVID-19 vaccine.

But you should still know the symptoms to look out for.

Get urgent medical help if you get any of these symptoms in the weeks after the AstraZeneca COVID-19 vaccine:

  • breathlessness
  • pain in the chest or stomach
  • leg swelling
  • severe or worsening headache or blurred vision
  • persistent bleeding, under the skin where there was no previous injury
  • multiple small bruises, reddish or purplish spots, or blood blisters under the skin

No need to take aspirin

You do not need to take aspirin before or after vaccination. These are very rare blood clotting conditions and aspirin would not have a beneficial effect.

Serious side effects

Serious side effects, like a severe allergic reaction, are extremely rare.

Serious side effects after the AstraZeneca vaccine are seen in approximately 1 in 100,000 people.

Your vaccinator is trained to treat any serious allergic reactions.

Fever after COVID-19 vaccines

It’s common to develop a fever (temperature of 38 degrees Celsius or above) after any vaccination. This usually happens within 2 days (48 hours) of getting the vaccine. It usually goes away within 2 days.

You are more likely to get a fever after the second dose of your vaccine.

If you feel uncomfortable, take paracetamol or ibuprofen following the instructions on the box or leaflet. 

If your fever starts more than 2 days after you are vaccinated, or lasts longer than 2 days, you should self-isolate (stay in your room). Phone your GP to arrange a COVID-19 test.

Updates on COVID-19 vaccine side effects

The COVID-19 vaccines have gone through the same clinical trials and safety checks as all other licensed vaccines. But these vaccines are new and long-term side effect information is limited.

As more people in Ireland and around the world get vaccinated, more information on side effects may become available.

We will update this page with any new information.

If you develop COVID-19 symptoms after your vaccine

COVID-19 vaccines cannot give you COVID-19.

It is possible to have caught COVID-19 before getting your vaccine and not realise you have the symptoms until after your vaccination.

If you have symptoms after the first dose of your COVID-19 vaccine, you still need to have the second dose. While you may get some protection from the first dose, having the second dose will give you the best protection against the virus.

Self-isolate and phone a GP to arrange a COVID-19 test if you have a fever which:

  • starts more than 2 days after you get your vaccine
  • lasts longer than 2 days after you get your vaccine

If you have any common symptoms of COVID-19, it's important to self-isolate (stay in your room) and arrange a test to find out if you have COVID-19.

Read about what happens during the COVID-19 test

Reporting side effects of COVID-19 vaccines

As with all vaccines, you can report suspected side effects to the Health Products Regulatory Authority (HPRA).

There are 2 ways you can report a suspected adverse reaction to a COVID-19 vaccine:

As much information as is known should be provided, and where possible, the vaccine batch number should be included. You'll find this on your vaccine record card.

You can also ask your doctor or a family member to report side effects for you.

The HPRA cannot provide clinical advice on individual cases. Talk to your doctor or pharmacist about any medical concerns you may have.

Read more about reporting vaccine side effects to the HPRA

Use of AstraZeneca COVID-19 vaccine restarted

Use of the AstraZeneca COVID-19 vaccine has been restarted after a short pause.

The AstraZeneca COVID-19 vaccine is safe and effective. Go to your appointment if this vaccine is offered to you.

Read more about the restart of AstraZeneca COVID-19 vaccinations

This content was fact checked by vaccine experts working in Ireland

More information

COVID-19 vaccine AstraZeneca – European Medicines Agency

Last updated: 8 April 2021 at 12.05pm