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Side effects of statins

Like all medicines, statins can cause side effects. But not everyone gets them.

Talk to your GP or pharmacist if side effects bother you or do not go away.

Common side effects

Things you can do to help with common side effects of statins include:

Headaches

Make sure you rest and drink plenty of fluids. Try not to drink too much alcohol. Ask your pharmacist to recommend a painkiller.

Talk to your GP if the headaches last longer than a week or are severe.

Aches and pains

Gently stretch your muscles regularly. Ask your pharmacist to recommend a painkiller.

Have a warm bath with bath salts to soothe your muscles. Use ice packs and warm water bottle.

Contact your GP if your symptoms continue for more than a few days or get worse.

Feeling sick (nausea)

Stick to simple meals and do not eat rich or spicy food. It might help to take your statin after a meal or snack.

Getting sick (vomiting)

Try small, frequent sips of water if you're getting sick to avoid dehydration. Signs of dehydration include peeing less than usual or having dark, strong-smelling pee.

If you take the combined contraceptive pill or the progestogen-only pill and you're getting sick, your contraception may not protect you from pregnancy. Check the pill packet for advice.

Feeling weak or dizzy

If your statin makes you feel dizzy or weak, stop what you're doing and sit or lie down until you feel better. Try not to drink alcohol as it will make you feel worse. Do not drive, cycle or use tools or machinery if you're feeling weak or dizzy.

Nosebleeds

If you get a nosebleed, sit down and lean forward, with your head tilted forward. Pinch your nose just above your nostrils for 10 to 15 minutes and breathe through your mouth.

You could also try holding an icepack (or a bag of frozen peas wrapped in a tea towel) on the top of your nose to help reduce the blood flow.

Contact your GP if you are getting nosebleeds often.

Sore mouth or throat

Paracetamol can help with the pain. Gargling with warm, salty water may also help. Drink plenty of water, eat cool or soft foods, and avoid smoking or smoky places.

Pharmacies and supermarkets sell other types of medicated lozenges that contain either a local anaesthetic or antiseptic. This may help with pain.

For a sore throat, see your GP if it does not improve after a week. You may need a different treatment.

Cold-like symptoms

Drink plenty of liquids, rest if you can and eat healthily.

Talk to your pharmacist about products and medicines that will help.

Tell them you are taking a statin.

Constipation or farting

Try to eat smaller meals. Eat more high-fibre foods such as fresh fruit, vegetables and cereals, and drink plenty of water.

Drinking peppermint tea can be helpful for farting. Try to exercise more regularly, for example, by going for a daily walk or run.

If this does not help, talk to your pharmacist or GP.

Stomach pain

Try to rest and relax. It can help to eat and drink slowly and have smaller and more frequent meals. Putting a heat pad or covered hot water bottle on your stomach may also help.

If these symptoms carry on, or if you're in a lot of pain, speak to your pharmacist or GP.

Diarrhoea

Drink plenty of water or other fluids to avoid dehydration. Signs of dehydration include peeing less than usual or having dark, strong-smelling pee. Do not take any medicines to treat diarrhoea without speaking to a pharmacist or GP.

If you're taking the combined contraceptive pill or progestogen-only pill and you have severe diarrhoea for more than 24 hours, your contraception may not protect you from pregnancy. Check the pill packet for advice.

Indigestion

It might help to eat smaller and more frequent meals, and to eat and drink slowly. Talk to your GP if the symptoms get worse.

See the patient information leaflet that comes with your medicine for a full list of side effects.

Non-urgent advice: Find your patient information leaflet

Your patient information leaflet is the leaflet that comes with your medicine. You can find a digital version of the leaflet online.

Report side effects

You can report any suspected side effects to the Health Products Regulatory Authority (HPRA): report an issue - hpra.ie

Serious side effects

Serious side effects (anaphylaxis) with statins are rare.

Urgent advice: Contact a GP urgently if you have:

  • muscle pain, weakness or cramp
  • a high temperature of 38 degrees and above
  • yellowing of your skin or white of your eyes
  • dark pee
  • pale poo
  • a severe rash with peeling, swelling and pink-red blotches
  • severe stomach pain
  • a cough or shortness of breath
  • weight loss
  • unusual bleeding or bruising
  • double vision or drooping eyelids
  • problems swallowing

Stop taking your statins immediately if you have any of these symptoms.

Serious allergic reaction

In rare cases it's possible to have a serious allergic reaction to statins.

Emergency action required: Call 112 or 999 or go to an emergency department (ED) if:

  • you get a rash that is itchy, red, swollen, blistered or peeling
  • you are wheezing
  • you get tightness in your chest or throat
  • you have trouble breathing or talking
  • your mouth, face, lips, tongue or throat start swelling

Page last reviewed: 12 June 2024
Next review due: 12 June 2027